Coronavirus:

[Roy]

...I seriously doubt that what the S. Koreans did would be possible to do here w/o rioting in the streets, etc.

What did they do, that would bring that on?

[Rufus T. Firefly]

...I seriously doubt that what the S. Koreans did would be possible to do here w/o rioting in the streets, etc.

What did they do, that would bring that on?

Take our version of lock down and make it seriously real and enforced across the nation. We're not a population that takes orders well; we already have a segment of our population that's in partial revolt despite all good indications that closing down is working and keeping our medical infrastructure from becoming overwhelmed, and being able to be fully prepared to respond despite the lack of support and supplies that the Fed Gov't should be providing. SC, TN, etc.....well, maybe they will get lucky.

[up148]

Common sense is very uncommon these days. So, expecting many to know and do the right thing just doesn't happen. People seem to have a hard time connecting the dots these days.

[Rufus T. Firefly]

Common sense is very uncommon these days. So, expecting many to know and do the right thing just doesn't happen. People seem to have a hard time connecting the dots these days.

True. And many just go where the herd is pointed w/o giving it any rational thought whatsoever.....

[Rufus T. Firefly]

[HONDO74]

If this is true will they actually be able to develop a vaccine that will work

Coronavirus has mutated into at least 30 different strains, Chinese study finds
https://nypost.com/2020/04/21/coronavir ... ins-study/

The novel coronavirus has mutated into at least 30 different genetic variations, according to a new study in China.

The results showed that medical officials have vastly underestimated the overall ability of the virus to mutate, in finding that different strains have affected different parts of the world, leading to potential difficulties in finding an overall cure.

The study, which was carried out by professor Li Lanjuan and colleagues from Zhejiang University in Hangzhou, China, was published in a non-peer reviewed paper released on Sunday.

The researchers analyzed the strains from 11 randomly chosen coronavirus patients from Hangzhou, where there have been 1,264 reported cases, and then tested how efficiently they could infect and kill cells. China’s coronavirus numbers, however, have been questioned, as they have not been verified.

More than 30 different mutations of the virus were detected, of which 19 were previously undiscovered.

“Sars-CoV-2 has acquired mutations capable of substantially changing its pathogenicity,” Li wrote in the paper.

As of Tuesday afternoon, COVID-19 has infected more than 804,000 people in the United States and killed at least 43,200. More than 4 million tests have been conducted in the US, but experts believe that number must be increased in order to reopen society. Worldwide, there are at least 2.5 million cases of the disease.

Li’s team found that some of the most aggressive strains of the virus were able to generate 270 times the viral load as the weakest strains; in addition, the aggressive strains killed the human cells fastest.

According to their findings, the “true diversity” of the viral strains is underappreciated and must be understood in order to find a treatment or vaccine.

“Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations, especially the founding mutations, into account to avoid potential pitfall,” the authors wrote.

[Rufus T. Firefly]

If this is true will they actually be able to develop a vaccine that will work

Coronavirus has mutated into at least 30 different strains, Chinese study finds

The study, which was carried out by professor Li Lanjuan and colleagues from Zhejiang University in Hangzhou, China, was published in a non-peer reviewed paper released on Sunday.

That non-reviewed aspect immediately casts doubt on the veracity and quality of the study.

The researchers analyzed the strains from 11 randomly chosen coronavirus patients from Hangzhou, where there have been 1,264 reported cases, and then tested how efficiently they could infect and kill cells. China’s coronavirus numbers, however, have been questioned, as they have not been verified.

11 seems a low sampling number to arrive at a conclusion of at least 30 different strains......and then which one or ones are actually really even dangerous

“Sars-CoV-2 has acquired mutations capable of substantially changing its pathogenicity,” Li wrote in the paper.

No surprise at all - what is not clear is in what way it is changed; less or more dangerous.

Will there be a vaccine? Unknown. Last I looked there were at least 9 different companies pursuing DNA or mRNA based vaccines into trials. One was pursuing a polyclonal antibody strategy.

As of Tuesday afternoon, COVID-19 has infected more than 804,000 people in the United States and killed at least 43,200. More than 4 million tests have been conducted in the US, but experts believe that number must be increased in order to reopen society. Worldwide, there are at least 2.5 million cases of the disease.

Yet the US rushes to re-open w/o adequate testing, and reliable containment behavior.

Li’s team found that some of the most aggressive strains of the virus were able to generate 270 times the viral load as the weakest strains; in addition, the aggressive strains killed the human cells fastest.

According to their findings, the “true diversity” of the viral strains is underappreciated and must be understood in order to find a treatment or vaccine.

“Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations, especially the founding mutations, into account to avoid potential pitfall,” the authors wrote.

Pretty obvious.....but I'd discount that statement regarding diversity being underappreciated; the virologists that are working in this area certainly appreciate mutation potential.

[Rufus T. Firefly]

[MurphOnMillerAve]

Yeah, I'll bet that helped .

[Rufus T. Firefly]

Yeah, I'll bet that helped .

You might be missing the irony - Pericles..........who died of plague......

[chuck]

You might be missing the irony - Pericles..........who died of plague......

Better late than never!

[HONDO74]

Yeah, I'll bet that helped .

You might be missing the irony - Pericles..........who died of plague......

Pericles
https://en.wikipedia.org/wiki/Pericles

He, along with several members of his family, succumbed to the Plague of Athens in 429 BC, which weakened the city-state during a protracted conflict with Sparta.

The exact identity of the disease is uncertain, typhus or typhoid fever are suspected, but this has been the source of much debate. In any case, the city's plight, caused by the epidemic, triggered a new wave of public uproar, and Pericles was forced to defend himself in an emotional final speech,

This is considered to be a monumental oration, revealing Pericles' virtues but also his bitterness towards his compatriots' ingratitude. Temporarily, he managed to tame the people's resentment and to ride out the storm, but his internal enemies' final bid to undermine him came off; they managed to deprive him of the generalship and to fine him at an amount estimated between 15 and 50 talents.

Nevertheless, within just a year, in 429 BC, the Athenians not only forgave Pericles but also re-elected him as strategos. He was reinstated in command of the Athenian army and led all its military operations during 429 BC, having once again under his control the levers of power

[MurphOnMillerAve]

Yeah, I'll bet that helped .

You might be missing the irony - Pericles..........who died of plague......

Who missed the irony ?

[Rufus T. Firefly]

Yeah, I'll bet that helped .

You might be missing the irony - Pericles..........who died of plague......

Who missed the irony ?

Anyone who was unaware that that was Pericles being hosed down with disinfectant.

[HONDO74]

US health official warns of dangerous second wave
https://www.bbc.com/news/world-us-canada-52378845

A second wave of coronavirus cases in the US could be even worse than the first, the country's top health official has warned.

Centers for Disease Control and Prevention (CDC) director Robert Redfield said the danger was higher as a fresh outbreak would likely coincide with the flu season.

It would put "unimaginable strain" on the US health care system, he said.

The US has seen more than 800,000 cases - the highest in the world.

More than 45,000 people have so far died with coronavirus across the US, according to a tally kept by Johns Hopkins University.

California had its highest one-day rise in new cases on Monday while New Jersey, the worst-hit US state apart from New York, saw its highest increase in deaths in one day.