vaccine

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Rufus T. Firefly
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Re: vaccine

Postby Rufus T. Firefly » Fri Dec 11, 2020 10:21 am

robert. wrote:If they can vaccinate 3 million people a month. 36 million a year. That takes us to 2028. To get the job done


If all remains constant, almost true; subtract out all under 16 years old and all the refusniks.

But, Moderna goes before the review committee soon. Also, Astra-Zenica will probably get to a review committee next year as will others, like J&J. There were at one point 200 different vaccines being developed and/or in trials.

There's more than 1 egg in the basket.
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Neil
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Re: vaccine

Postby Neil » Fri Dec 11, 2020 10:51 am

Most experts are predicting that everyone who wants a vaccine will be able to receive at least one dose by late spring or early summer. Many more vaccines in the pipeline than just the Pfizer and Moderna mRNA vaccines.

Allergic, moderate reactions to vaccines are not rare, so the two English vaccine recipients with so-called anaphylactoid reactions are neither surprising nor particularly worrisome.
Neil

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rogruth
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Re: vaccine

Postby rogruth » Fri Dec 11, 2020 12:27 pm

If the vaccine we are hearing the most about takes two doses, how much time can be between doses to still be effective?
roger

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chuck
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Re: vaccine

Postby chuck » Fri Dec 11, 2020 12:39 pm

If the vaccine we are hearing the most about takes two doses, how much time can be between doses to still be effective?


The original plan was for two doses approximately three to four weeks apart. They are re-analyzing the data. It may be that one dose is enough and that the vaccine starts "working" in days, not weeks. The second dose was partially to verify that it was working (that's why you get a more pronounced reaction to the second dose).
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Re: vaccine

Postby Neil » Fri Dec 11, 2020 12:39 pm

2-4 weeks between doses. Protection is detectable after the first dose (10 days or so) and no severe cases are seen in the vaccine recipients.
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rogruth
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Re: vaccine

Postby rogruth » Fri Dec 11, 2020 12:57 pm

Then one dose may be enough?
Or not known at this time?
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chuck
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Re: vaccine

Postby chuck » Fri Dec 11, 2020 1:01 pm

Designed for two, that's what's approved and that's what they will initially go on. The more detailed analysis of the data may show second shot is not required.
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Rufus T. Firefly
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Re: vaccine

Postby Rufus T. Firefly » Fri Dec 11, 2020 1:04 pm

chuck wrote:Designed for two, that's what's approved and that's what they will initially go on.


Have not heard that the FDA has actually approved it yet.

The more detailed analysis of the data may show second shot is not required.


The continuing clinical trials, plus the follow up of the use under the pending approval will generate a lot more data.
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chuck
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Re: vaccine

Postby chuck » Fri Dec 11, 2020 1:11 pm

Once I built a railroad, I made it run,
Made it race against time.
Once I built a railroad, now it's done --
Brother, can you spare a dime?

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Rufus T. Firefly
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Re: vaccine

Postby Rufus T. Firefly » Fri Dec 11, 2020 1:13 pm

chuck wrote:According to the Times, this evening they will give the go-ahead


Right, the Times has ears inside the FDA. Lovely. And once again, Trump demonstrates just how painfully ignorant he is...............I'm not sure I've ever seen the FDA move this fast on anything.
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chuck
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Re: vaccine

Postby chuck » Fri Dec 11, 2020 3:23 pm

Once I built a railroad, I made it run,
Made it race against time.
Once I built a railroad, now it's done --
Brother, can you spare a dime?

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Rufus T. Firefly
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Re: vaccine

Postby Rufus T. Firefly » Fri Dec 11, 2020 3:57 pm



Sad for Steve. Good man and a good doc.
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chuck
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Re: vaccine

Postby chuck » Fri Dec 11, 2020 5:43 pm

Sad for Steve. Good man and a good doc.


Yes. Like a lot of other people that USED to work in the administration. They either got disgusted and left or were tweeted out the door when they where "disloyal" to the occupant in the Oval Office by being loyal to their oaths of office and the American people.
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E7
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Re: vaccine

Postby E7 » Fri Dec 11, 2020 10:04 pm

Too bad we can't get a survey from all the people that have died from this crap about the speed things are moving at.

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Rufus T. Firefly
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Re: vaccine

Postby Rufus T. Firefly » Sat Dec 12, 2020 9:45 am

E7 wrote:Too bad we can't get a survey from all the people that have died from this crap about the speed things are moving at.


Too bad that they and the 3000+ that are dying every day from what might have been largely controlled have died from what has effectively been negligence. I'm not aware of any drug ever being created, put through phase 1-3 trials and taken to the FDA in under a year, and then given an emergency use approval this fast in history. Emergency use approval btw is not broad approval of a drug - limited to specific indications and essentially still in a giant clinical trial.

I was on the phone last night with my 84 year old aunt in PA were she was telling me that my cousin and his wife have it and are terrible sick, that people there are dying or waiting to die on ventilators. She's terrified and alone. Not a thing I can do except call here every so many days to check on her.

When this hits home, hits family and friends, and then reality is at your doorstep, maybe, maybe, maybe, just maybe people will take things seriously.

Watched part of the committee review and all; watched the FDA commish this morning; we have several very bad months (maybe most of 2021 even) ahead and vaccines are not magic wands and diseases do not just magically go away.
What if lollipops moaned every time we licked them?


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